Prescription drugs info

It is very important that your doctor check your progress at regular visits, to allow for changes in your dose and to help reduce any side effects .

Do not take Celexa with or within 14 days of taking an MAO inhibitor (e.g., isocarboxazid [Marplan®], phenelzine [Nardil®], procarbazine [Matulane®], selegiline [Eldepryl®], tranylcypromine [Parnate®]). Do not take an MAO inhibitor within 14 days of taking Celexa. If you do, you may have extremely high blood pressure or convulsions (seizures) .

Make sure your doctor knows about all the other medicines you are using. Celexa may cause a serious condition called serotonin syndrome when taken with some medicines. Do not use Celexa with linezolid (e.g., Zyvox®), lithium, tryptophan, St. John’s Wort, or some pain or migraine medicines (e.g., tramadol [Ultram®], sumatriptan [Imitrex®], zolmitriptan [Zomig®], or rizatriptan [Maxalt®]). Check with your doctor first before taking any other medicines, including pimozide (Orap®) .

Celexa may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you, your child, or your caregiver notice any of these side effects, tell your doctor or your child’s doctor right away .

Avoid drinking alcoholic beverages while you are taking Celexa .

Celexa may cause some people to become drowsy, to have trouble thinking, or to have problems with movement. Make sure you know how you react to Celexa before you drive, use machines, or do anything else that could be dangerous if you are not alert or well-coordinated.

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Take Celexa only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered .

Celexa may be taken with or without food. If your doctor tells you to take it at a specific time, follow your doctor’s instructions .

If you are using the oral liquid form of Celexa, shake the bottle well before measuring each dose. Use a marked measuring spoon, oral syringe or medicine cup to measure each dose .

You may have to take Celexa for 4 weeks before you begin to feel better. Your doctor will check your progress at regular visits during this time. Also, you may need to keep taking Celexa for 6 months or longer to help prevent the return of the depression .

Do not stop taking Celexa without checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely to prevent side effects .

Celexa Dosing
The dose of Celexa will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount Celexa that you take depends on the strength of Celexa. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take Celexa depend on the medical problem for which you are using Celexa.

* For oral dosage form (solution and tablets):
o For depression:
+ Adults and adolescents—At first, 20 milligrams (mg) once a day, taken either in the morning or evening. Your doctor may increase your dose gradually if needed. However, the dose usually is not more than 60 mg a day.
+ Children—Use and dose must be determined by your doctor.
+ Older adults—At first, 20 milligrams (mg) once a day, taken either in the morning or evening. Your doctor may increase your dose gradually if needed. However, the dose usually is not more than 40 mg a day .

Celexa Missed Dose
If you miss a dose of Celexa, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Celexa Storage
Store Celexa in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

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Celexa is used to treat mental depression .

Celexa belongs to a group of medicines known as selective serotonin reuptake inhibitors (SSRIs). These medicines are thought to work by increasing the activity of the chemical serotonin in the brain .

Celexa is available only with your doctor’s prescription.

Commonly used brand name(s):

In the U.S.
* Celexa

Celexa Available Dosage Forms:
* Tablet
* Solution

Celexa Therapeutic Class: Antidepressant
Celexa Pharmacologic Class: Serotonin Reuptake Inhibitor

Oral routeTabletSolution

* Suicidality and Antidepressant Drugs
* Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of citalopram hydrobromide or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Citalopram hydrobromide is not approved for use in pediatric patients.

Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies with major depressive disorder (MDD) and other psychiatric disorders. Short term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24, and there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. This risk must be balanced with the clinical need. Monitor patients closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Not approved for use in pediatric patients.

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Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

* Symptoms of Celexa overdose may include:
Amnesia, bluish or purplish discoloration of the skin, coma, confusion, convulsions, dizziness, drowsiness, hyperventilation, nausea, rapid heartbeat, sweating, tremor, vomiting

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ADULTS

The recommended starting dose of Celexa tablets or oral solution is 20 milligrams once a day. Dosage is usually increased to 40 milligrams once daily after at least a week has passed. Do not exceed 40 milligrams a day.

For older adults and those who have liver problems, the recommended dose is 20 milligrams once a day.

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The effects of Celexa during pregnancy have not been adequately studied, and the potential for harm has not been ruled out. If you are pregnant or plan to become pregnant while on Celexa therapy, tell your doctor immediately.

Celexa appears in breast milk and will affect the nursing infant. You should consider discontinuing either breastfeeding or Celexa. Talk with your doctor about the pros and cons of each option.

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Celexa does not increase the effects of alcohol. Nevertheless, it’s considered unwise to combine Celexa with alcohol or any other drug that affects the brain. (Be particularly careful to avoid MAO inhibitors.)

If Celexa is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Tell your doctor about any prescription or over-the-counter drugs you are planning to take, and be especially certain to check with him before combining Celexa with the following:

Carbamazepine
Cimetidine
Erythromycin
Fluconazole
Itraconazole
Ketoconazole
Lithium
Metoprolol
Omeprazole
Other antidepressants such as amitriptyline, desipramine, imipramine, and nortriptyline
Sumatriptan
Warfarin

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In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Celexa, or any other antidepressant in a child or adolescent, must balance this risk with the clinical need. Celexa has not been studied in children or adolescents and is not approved for treating anyone less than 18 years old.

Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they are taking antidepressants. Individuals being treated with Celexa and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly—especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior—and report them to the doctor immediately. Be especially observant at the beginning of treatment or whenever there is a change in dose.

In recommended doses, Celexa does not seem to impair judgment or motor skills. However, a theoretical possibility of such problems remains, so you should use caution when driving or operating dangerous equipment until you are certain of Celexa’s effect.

There is a slight chance that Celexa will trigger a manic episode. Use Celexa with caution if you suffer from manic-depression (bipolar disorder). Use caution, too, if you are over 60 years old, have liver or kidney problems, suffer from heart disease or high blood pressure, or have ever had seizures.

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If Celexa gives you an allergic reaction, you cannot continue using it. Also remember that Celexa must never be combined with an MAO inhibitor.

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Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Celexa.

* Celexa Side effects may include:
Abdominal pain, agitation, anxiety, diarrhea, drowsiness, dry mouth, ejaculation disorders, fatigue, impotence, indigestion, insomnia, loss of appetite, nausea, painful menstruation, respiratory tract infection, sinus or nasal inflammation, sweating, tremor, vomiting

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