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Amoxicillin Description

October 11th, 2009 Leave a comment Go to comments

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Amoxicillin and other antibacterial drugs, Amoxicillin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

Formulations of Amoxicillin capsules, USP contain Amoxicillin, a semisynthetic antibiotic, an analog of ampicillin, with a broad spectrum of bactericidal activity against many gram-positive and gram-negative microorganisms. Chemically, it is (2S,5R,6R) – 6 – [(R) - ( - ) - 2 - amino - 2 - (p - hydroxyphenyl)acetamido] – 3,3 – dimethyl – 7 – oxo – 4 – thia – 1 – azabicyclo[3.2.0]heptane – 2 – carboxylic acid trihydrate.

The Amoxicillin molecular formula is C16H19N3O5S•3H2O, and the molecular weight is 419.45.

Capsules of Amoxicillin are intended for oral administration.

Each capsule of Amoxicillin with blue cap and pink body, contains 250 mg or 500 mg Amoxicillin as the trihydrate.  The body of the 250 mg capsule is imprinted with ‘A44’ in black ink.  The body of the 500 mg capsule is imprinted with ‘A45’ in black ink.  Inactive ingredients:  microcrystalline cellulose, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin, magnesium stearate, titanium dioxide, and sodium lauryl sulfate.
 
Meets USP Dissolution Test 2.

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