Some medical conditions may interact with Carisoprodol . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
* if you are pregnant, plan to become pregnant, or are breast-feeding
* if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
* if you have allergies to medicines or other substances
* if you have a history of kidney or liver problems, prostate problems, or seizures
* if you have a history of alcohol or other substance abuse or dependence
Some MEDICINES MAY INTERACT with Carisoprodol . Tell your health care provider if you are taking any other medicines, especially any of the following:
* Benzodiazepines (eg, alprazolam), opioid analgesics (eg, hydrocodone), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because severe drowsiness and prolonged sleep may occur
* Fluvoxamine, meprobamate, or omeprazole because they may increase the risk of Carisoprodol ’s side effects
* Rifampin or St. John’s wort because they may decrease Carisoprodol ’s effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if Carisoprodol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
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* you are allergic to any ingredient in Carisoprodol or to similar medicines (eg, meprobamate)
* you have the blood disorder porphyria
* you take sodium oxybate (GHB) or meprobamate
Contact your doctor or health care provider right away if any of these apply to you.
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Treating discomfort associated with certain painful muscle conditions. It is usually used along with rest and physical therapy.
Carisoprodol is a skeletal muscle relaxant. It works in the brain and spinal cord to relax the muscles. It also causes drowsiness.
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On very rare occasions, the first dose of Carisoprodol has been followed by idiosyncratic symptoms appearing within minutes or hours. Symptoms reported include: extreme weakness, transient quadriplegia, dizziness, ataxia, temporary loss of vision, diplopia, mydriasis, dysarthria, agitation, euphoria, confusion, and disorientation. Symptoms usually subside over the course of the next several hours. Supportive and symptomatic therapy, including hospitalization, may be necessary.
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In postmarketing experience, cases of drug abuse, dependence and withdrawal have been reported. Carisoprodol should be used with caution in addiction prone individuals.
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Patients should be warned that Carisoprodol may have sedative properties and may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a motor vehicle or operating machinery.
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Occasionally, within the period of the first to fourth dose of Carisoprodol allergic reactions have occurred in patients who have had no previous contact with the drug. Skin rash, erythema multiforme, pruritus, eosinophilia, and fixed drug eruption have been reported with Carisoprodol with cross reaction to meprobamate. Severe reactions have been manifested by asthmatic episodes, fever, weakness, dizziness, angioneurotic edema, smarting eyes, hypotension, and anaphylactoid shock.
In case of allergic or idiosyncratic reactions to Carisoprodol, discontinue the drug and initiate appropriate symptomatic therapy, which may include epinephrine, antihistamines, and in severe cases corticosteroids.
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The safety of Carisoprodol in pregnancy or lactation has not been established. Therefore, use of Carisoprodol in pregnancy, in nursing mothers, or in women of childbearing potential requires that the potential benefits of Carisoprodol be weighed against the potential hazards to mother and child. Carisoprodol is present in breast milk of lactating mothers at concentrations two to four times that of maternal plasma. This factor should be taken into account when use of Carisoprodol is contemplated in breast-feeding patients.
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Carisoprodol Tablets are contraindicated in patients with acute intermittent porphyria, and in patients who are allergic to or who have had idiosyncratic reactions to Carisoprodol or meprobamate related compounds.
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Carisoprodol Tablets, USP are available as 350 mg round, white tablets. Carisoprodol is (±)-2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate. Carisoprodol is a white, crystalline powder, having a mild, characteristic odor and a bitter taste. It is very slightly soluble in water; freely soluble in alcohol, in chloroform, and in acetone; its solubility is practically independent of pH. Carisoprodol is present as a recemic mixture.
Other Carisoprodol ingredients
Carisoprodol Tablets, USP-croscarmellose sodium, hydrogenated vegetable oil, hypromellose, magnesium stearate and microcrystalline cellulose.
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