In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Celexa, or any other antidepressant in a child or adolescent, must balance this risk with the clinical need. Celexa has not been studied in children or adolescents and is not approved for treating anyone less than 18 years old.
Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they are taking antidepressants. Individuals being treated with Celexa and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly—especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior—and report them to the doctor immediately. Be especially observant at the beginning of treatment or whenever there is a change in dose.
In recommended doses, Celexa does not seem to impair judgment or motor skills. However, a theoretical possibility of such problems remains, so you should use caution when driving or operating dangerous equipment until you are certain of Celexa’s effect.
There is a slight chance that Celexa will trigger a manic episode. Use Celexa with caution if you suffer from manic-depression (bipolar disorder). Use caution, too, if you are over 60 years old, have liver or kidney problems, suffer from heart disease or high blood pressure, or have ever had seizures.
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Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Celexa.
* Celexa Side effects may include:
Abdominal pain, agitation, anxiety, diarrhea, drowsiness, dry mouth, ejaculation disorders, fatigue, impotence, indigestion, insomnia, loss of appetite, nausea, painful menstruation, respiratory tract infection, sinus or nasal inflammation, sweating, tremor, vomiting
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Celexa is available in tablet and liquid forms. Take either formulation once a day, in the morning or evening, with or without food. Although your depression will begin to lift in 1 to 4 weeks, you should continue taking Celexa regularly. It takes several months for the medication to yield its full benefits.
* If you miss your Celexa dose…
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.
*Celexa Storage instructions…
Store at room temperature.
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Be careful to avoid taking Celexa for 2 weeks before or after using an antidepressant known as an MAO inhibitor. Drugs in this category include phenelzine sulfate and tranylcypromine sulfate. Combining Celexa with one of these medications could lead to a serious—even fatal—reaction.
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Celexa is used to treat major depression—a stubbornly low mood that persists nearly every day for at least 2 weeks and interferes with everyday living. Symptoms may include loss of interest in your usual activities, insomnia or excessive sleeping, a change in weight or appetite, constant fidgeting or a slowdown in movement, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and repeated thoughts of suicide.
Like the antidepressant medications fluoxetine hydrochloride, paroxetine hydrochloride, and sertraline, Celexa is thought to work by boosting serotonin levels in the brain. Serotonin, one of the nervous system’s primary chemical messengers, is known to elevate mood.
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* If you have any questions about Celexa , please talk with your doctor, pharmacist, or other health care provider.
* Celexa is to be used only by the patient for whom it is prescribed. Do not share it with other people.
* If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Celexa . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
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Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately. Symptoms may include blue skin or lips; coma; confusion; fast breathing; fast, slow, or irregular heartbeat; memory loss; muscle pain; seizures; severe or persistent dizziness, drowsiness, nausea, or vomiting; tremor.
Proper storage of Celexa :
Store Celexa at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Celexa out of the reach of children and away from pets.
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All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Decreased sexual desire or ability; diarrhea; dizziness; drowsiness; dry mouth; increased sweating; lightheadedness when you stand or sit up; loss of appetite; nausea; stuffy nose; tiredness.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); absent menstrual period; bizarre behavior; black or bloody stools; chest pain; confusion; decreased concentration; decreased coordination; fainting; fast or irregular heartbeat; hallucinations; memory loss; new or worsening agitation, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, or inability to sit still; persistent, painful erection; red, swollen, blistered, or peeling skin; seizures; severe or persistent anxiety or trouble sleeping; severe or persistent headache; stomach pain; suicidal thoughts or attempts; tremor; unusual bruising or bleeding; unusual or severe mental or mood changes; unusual weakness; vision changes; worsening of depression.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
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* Celexa may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Celexa with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
* Do not drink alcohol while you are using Celexa .
* Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Celexa ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
* One to 4 weeks may pass before your symptoms improve. Do NOT take more than the recommended dose, change your dose, or use Celexa for longer than prescribed without checking with your doctor.
* Children, teenagers, and young adults who take Celexa may be at increased risk for suicidal thoughts or actions. Watch all patients who take Celexa closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
* Celexa and a medicine called escitalopram have the same active ingredient. Do not take Celexa if you are also taking escitalopram.
* If your doctor tells you to stop taking Celexa , you will need to wait for several weeks before beginning to take certain other medicines (eg, MAOIs, nefazodone). Ask your doctor when you should start to take your new medicines after you have stopped taking Celexa.
* Celexa may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
* Serotonin syndrome is a possibly fatal syndrome that can be caused by Celexa . Your risk may be greater if you take Celexa with certain other medicines (eg, “triptans,” MAOIs). Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.
* Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Celexa . Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.
* Use Celexa with caution in the ELDERLY; they may be more sensitive to its effects, especially low blood sodium levels.
* Caution is advised when using Celexa in CHILDREN; they may be more sensitive to its effects, especially increased risk of suicidal thoughts or actions.
* Celexa should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
* Celexa may cause weight changes. CHILDREN and teenagers may need regular weight and growth checks while they take Celexa .
* PREGNANCY and BREAST-FEEDING: Celexa may cause harm to the fetus if it is used during the last 3 months of pregnancy. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Celexa while you are pregnant. Celexa is found in breast milk. Do not breast-feed while taking Celexa.
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