Cialis contraindications
Cialis and Nitrates
Administration of Cialis to patients who are using any form of organic nitrate, either regularly and/or intermittently, is contraindicated. In clinical pharmacology studies, Cialis was shown to potentiate the hypotensive effect of nitrates. This is thought to result from the combined effects of nitrates and Cialis on the nitric oxide/cGMP pathway.
Cialis Hypersensitivity Reactions
Cialis is contraindicated in patients with a known serious hypersensitivity to tadalafil (Cialis or ADCIRCATM). Hypersensitivity reactions have been reported, including Stevens-Johnson syndrome and exfoliative dermatitis.
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